POLICE have launched an investigation after three people died and four were left injured all while wearing orange wristbands in Pennsylvania.
It is believed the medical emergency came from an isolated overdose from a “tainted, potentially deadly batch” of drugs, authorities said.
Five were found in a flat, one in a lift and one on the street.
The conditions of the four injured range from serious to critical.
Pittsburgh director of public safety Wendell Hissrich said all the victims are believed to be middle-aged men.
Officers found more than one venue in the city giving out orange wristbands for events.
The victims were at the same venue together and then went to the flat where they took the drugs at the same time and same location, police said.
They added it was an isolated incident and not a case of drugs being distributed at a large venue.
It is not yet known which of the events are connected to the mystery medical emergency.
Mr. Hissrich told the Pittsburgh-Gazette: “We have no indication there was a party (at the apartment).”
Commander Lando said investigators are speaking with the surviving victims at the hosptial to piece together what happened.
A police statement said: “The victims appear to have been at the same venue together, and then to have gone to a second location at a private residence where they apparently overdosed on drugs.
“The victims all took the narcotics at the same time and in the same location.
“To be clear, this was not a case of a tainted drug being passed around or distributed in large volume at a large venue which could have affected even more people.
“It appears to have been isolated to a single location.”
It added there could be “a tainted, potentially deadly batch of drugs in the community”.
Police raced to the scene in Pittsburgh responding to reports about an unconscious man at 2pm local time (6pm GMT).
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One man was found on the street and taken to hospital and another was found in a lift, but he later died.
A firm that represents the apartment building said none of the victims were residents of the building, but were acquaintances with one “good standing” resident.
He was not in the flat at the time the victims were found and it is unclear how they got into the building.
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